| Background of the antigen |
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. |
| Properties |
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-ICA12/SOX13 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| Synonyms |
ICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12. |
| Storage conditions |
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year. |
| Source |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICA12 |
| Cross-reactive species details |
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
| Long name |
ICA12/SOX13 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated |
| Specificity |
This is a highly specific antibody against ICA12/SOX13. |
| Also known as |
Anti-ICA12/SOX13 PAb ALEXA FLUOR 488 |
| Host Organism |
Rabbit (Oryctolagus cuniculus) |
| Category |
Conjugated Primary Antibodies |
| Purification |
Purified by Protein A. |
| Clone |
Polyclonal antibody |
| Recommended dilutions |
IF(IHC-P)(1:50-200) |
| Crossreactivity |
Human, Mouse, Rat |
| Conjugated with |
ALEXA FLUOR® 488 |
| Excitation emission |
499nm/519nm |
| Conjugation |
Alexa Fluor |
| Concentration |
1ug per 1ul |
| Target Antigen |
ICA12/SOX13 |
| Modification |
Unmodified |
| Clonality |
Polyclonal |
| Tested applications |
IF(IHC-P) |
| French translation |
anticorps |
| Modification Site |
None |
