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Background of the antigenSox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
SynonymsICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12.
PropertiesFor facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICA12
Cross-reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Long nameICA12/SOX13 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
SpecificityThis is a highly specific antibody against ICA12/SOX13.
Also known asAnti-ICA12/SOX13 PAb ALEXA FLUOR 594
Host OrganismRabbit (Oryctolagus cuniculus)
ConjugationAlexa Fluor,ALEXA FLUOR® 594
CategoryConjugated Primary Antibodies
PurificationPurified by Protein A.
ClonePolyclonal antibody
Recommended dilutionsIF(IHC-P)(1:50-200)
ConjugatedAlexa conjugate 1
CrossreactivityHuman, Mouse, Rat
Conjugated withALEXA FLUOR® 594
Target AntigenICA12/SOX13
Excitation emission590nm/617nm
Concentration1ug per 1ul
Tested applicationsIF(IHC-P)
French translationanticorps
Modification SiteNone