| Description |
The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. |
| Storage |
Aliquot the SOX-2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. |
| Species reactivity |
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur. |
| Properties |
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| Notes |
Titration of the SOX-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen |
A portion of amino acids 89-119 from the human protein was used as the immunogen for this SOX-2 antibody. |
| Recommended dilutions |
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50 |
| Intented use |
This SOX-2 antibodyis to be used only for research purposes and not for diagnostics.. |
| Concentration |
In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Host animal |
Rabbit (Oryctolagus cuniculus) |
| Clonality |
Polyclonal (rabbit origin) |
| Tested applications |
WB, IHC, IF, FACS, ELISA |
| Clone |
Polyclonal antibody |
| Conjugation |
Unconjugated |
| French translation |
anticorps |
| Purity |
Purified |
| Form |
Purified |
| Category |
Antibody |
| Uniprot # |
P48431 |
| Recognised antigen |
SOX-2 |
