| Antigen background |
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. |
| Properties |
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-ICA12/SOX13 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy. |
| Synonyms |
ICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12. |
| Storage conditions |
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year. |
| Crossreactive species details |
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
| Source |
KLH conjugated synthetic peptide derived from human ICA12 |
| Specificity |
This is a highly specific antibody against ICA12/SOX13. |
| Long name |
ICA12/SOX13 Polyclonal Antibody, Cy3 Conjugated |
| Purification method |
This antibody was purified via Protein A. |
| Host Organism |
Rabbit (Oryctolagus cuniculus) |
| Category |
Conjugated Primary Antibodies |
| Recommended dilutions |
IF(IHC-P)(1:50-200) |
| Excitation Emission |
512,550nm/570,615nm |
| Clone |
Polyclonal antibody |
| Additional conjugation |
cy3 conjugation kit |
| Crossreactivity |
Human, Mouse, Rat |
| Target Antigen |
ICA12/SOX13 |
| Concentration |
1ug per 1ul |
| Clonality |
Polyclonal |
| Modification |
Unmodified |
| Tested applications |
IF(IHC-P) |
| French translation |
anticorps |
| Modification site |
None |
| Conjugation |
Cy3 |
