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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity and cross-reactivityRecognizes human SOX12.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other namesSOX12 protein; Transcription factor SOX-12; transcription factor SOX-12; SOX-22 protein; SRY-related HMG-box gene 22; SRY (sex determining region Y)-box 12; Protein SOX-22
Purification methodAffinity Purified by Protein A affinity chromatography.
Form/AppearanceSupplied as a liquid in PBS, pH 7.2.
Tested applications:ELISA (EL/EIA), Western Blot (WB)
Gene nameSOX12; SOX12; SOX22; SOX22
Gene name synonimsSOX12; SOX12; SOX22; SOX22
Other gene namesSOX12; SOX12; SOX22; SOX22
Host organismMouse (Mus musculus)
Source organismHuman (Homo sapiens)
SubcategoryMnoclonal antibodies
Immunoglobulin isotypeIgG2b,k
Also known asSOX12