| Background of the antigen |
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. |
| Properties |
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-ICA12/SOX13 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| Synonyms |
ICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12. |
| Storage conditions |
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year. |
| Source |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICA12 |
| Cross-reactive species details |
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
| Long name |
ICA12/SOX13 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated |
| Specificity |
This is a highly specific antibody against ICA12/SOX13. |
| Also known as |
Anti-ICA12/SOX13 PAb ALEXA FLUOR 647 |
| Host Organism |
Rabbit (Oryctolagus cuniculus) |
| Category |
Conjugated Primary Antibodies |
| Conjugation |
Alexa Fluor,ALEXA FLUOR 647 |
| Purification |
Purified by Protein A. |
| Clone |
Polyclonal antibody |
| Recommended dilutions |
IF(IHC-P)(1:50-200) |
| Crossreactivity |
Human, Mouse, Rat |
| Conjugated with |
ALEXA FLUOR® 647 |
| Excitation emission |
650nm/665nm |
| Concentration |
1ug per 1ul |
| Target Antigen |
ICA12/SOX13 |
| Modification |
Unmodified |
| Clonality |
Polyclonal |
| Tested applications |
IF(IHC-P) |
| French translation |
anticorps |
| Modification Site |
None |
