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NameDescription
Antigen backgroundSox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
SynonymsICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12.
Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
SourceKLH conjugated synthetic peptide derived from human ICA12
SpecificityThis is a highly specific antibody against ICA12/SOX13.
Long nameICA12/SOX13 Polyclonal Antibody, Biotin Conjugated
Purification methodThis antibody was purified via Protein A.
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
Host OrganismRabbit (Oryctolagus cuniculus)
CategoryConjugated Primary Antibodies
ClonePolyclonal antibody
CrossreactivityHuman, Mouse, Rat
Additional conjugationBiotinylated
Concentration1ug per 1ul
Target AntigenICA12/SOX13
ClonalityPolyclonal
ModificationUnmodified
Tested applicationsWB, IHC-P
French translationanticorps
ConjugationBiotin
Modification siteNone
Excitation EmissionN/A