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NameDescription
Antigen backgroundSox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-ICA12/SOX13 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
SynonymsICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12.
Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
SourceKLH conjugated synthetic peptide derived from human ICA12
SpecificityThis is a highly specific antibody against ICA12/SOX13.
Long nameICA12/SOX13 Polyclonal Antibody, Cy3 Conjugated
Purification methodThis antibody was purified via Protein A.
Host OrganismRabbit (Oryctolagus cuniculus)
CategoryConjugated Primary Antibodies
Recommended dilutionsIF(IHC-P)(1:50-200)
Excitation Emission512,550nm/570,615nm
ClonePolyclonal antibody
Additional conjugationcy3 conjugation kit
CrossreactivityHuman, Mouse, Rat
Target AntigenICA12/SOX13
Concentration1ug per 1ul
ClonalityPolyclonal
ModificationUnmodified
Tested applicationsIF(IHC-P)
French translationanticorps
Modification siteNone
ConjugationCy3