| Background of the target antigen |
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. |
| Synonym names |
ICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12. |
| Properties |
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| Storage conditions |
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year. |
| Source |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICA12 |
| Cross reactive species details |
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
| Specificity |
This is a highly specific antibody against ICA12/SOX13. |
| Recommended dilutions |
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200) |
| Purification method |
This antibody was purified via Protein A. |
| Long name |
ICA12/SOX13 Primary Polyclonal Antibody |
| Tested Applications |
WB, IHC-P, IF(IHC-P) |
| Clone number |
Polyclonal antibody |
| Clonality |
Polyclonal antibody |
| Modification site(s) |
Unmodified antibody |
| Category |
Primary Antibodies |
| Cross reactivity |
Human, Mouse, Rat |
| Also known as |
ICA12/SOX13 PAb |
| Conjugation |
Unconjugated |
| Concentration |
1ug per 1ul |
| Target Antigen |
ICA12/SOX13 |
| French translation |
anticorps |
| Modification(s) |
None |
