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Product details

NameDescription
Background of the target antigenSox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
Synonym namesICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY Sex determining region Y-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determining region Y box 13; Transcription factor SOX 13; Transcription factor Sox-13; Type 1 diabetes autoantigen; Type 1 diabetes autoantigen ICA 12; Type 1 diabetes autoantigen ICA12.
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICA12
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
SpecificityThis is a highly specific antibody against ICA12/SOX13.
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Purification methodThis antibody was purified via Protein A.
Long nameICA12/SOX13 Primary Polyclonal Antibody
Tested ApplicationsWB, IHC-P, IF(IHC-P)
Clone numberPolyclonal antibody
ClonalityPolyclonal antibody
Modification site(s)Unmodified antibody
CategoryPrimary Antibodies
Cross reactivityHuman, Mouse, Rat
Also known asICA12/SOX13 PAb
ConjugationUnconjugated
Concentration1ug per 1ul
Target AntigenICA12/SOX13
French translationanticorps
Modification(s)None